Category Archives: Health News

ROLE OF GENETICS IN PROCESS OF AGING & ANTI-AGING

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The action of a single gene can have a big effect on how long a person lives. This may seem difficult to believe because so many factors go into determining life span, including a host of lifestyle factors and a long list of diseases. Nonetheless, remarkable effects on life span are seen when particular genes are deleted from a person’s genetic sequence. Furthermore, research, particularly involving microscopic roundworms, continues to provide scientists with tantalizing clues about the molecular pathways involved in aging.

Determination Of The Aging/Anti-Aging Gene

When studying genetic basis of aging, scientists tend to work with the other animals with a short life span; that way, they can observe the entire course of an organism’s existence and obtain relatively rapid experimental results e.g. Caenorhabditis elegans, a microscopic roundworm that typically lives to a ripe old age of two to three weeks. Another advantage of using C. elegans is that these worms have a simple physiology and easily manipulated genes. Scientists have found a number of genes in the organisms which are involved in aging process.

Similarly, now researchers who are working on human beings have found that people like Calment actually owe their longevity in their genes. The physician Thomas Perls and his colleagues at Boston University compared the genetic makeup of 801 Americans who were aged 95 to 119 years, with 926 of younger people. 300,000 points they took it under the microscope. They discovered that there is a kind of genetic pattern that unites the super old humans.

SIRT1: The Human Anti-aging Gene

Diet restriction and physical exercise is the basic requirement for the most diet and exercise programs. However, a severely restricted diet is not a good long-term solution for most people, scientists have been trying to find out ways to create the same results without actually cutting the calories.

Dr. Leonard P. Guarente, a biology professor at M.I.T., hit upon a potential answer when he was studying yeast cells. He found out the cells lived longer when they were given very small amounts of food, and Dr. Guarente started manipulating the cells’ genes to determine what part they played in the extended life span. When yeast cells undergoing caloric restriction were endowed with one certain gene, they lived even longer, and when that gene was eliminated by Dr. Guarente, the caloric restriction was for naught, and the yeast cells died. That gene was silent information regulator No. 2, or SIR2.

SIR2 appeared to stop the aging process by stopping the production of waste material in the cell, which allowed the cell to work better for longer. Dr. Guarente also performed this experiment on a roundworm with the same results.

Humans don’t have SIR2, but we have a gene that appears to do the same thing known as SIRT1. Both SIR2 and SIRT1 seem to work the same way in the body but of course in different organisms. They are charged with repairing the DNA within the body and suppressing certain genes. Suppression of genes is known as Gene silencing. This is important because if the wrong genes become activated, the cell’s function could be destroyed e.g. cells may develop a cancer. It may be that cases of Alzheimer’s and diabetes occur because of this type of genetic malfunction. Both of these diseases involve premature destruction of cells in certain parts of the body.

As we age, it becomes harder for SIR2 and SIRT1 (collectively known as sirtuins) to multi-task, so this gene silencing falls. As a result, we end up with the conditions we associate with older age, like cancers, heart diseases and the aforementioned Alzheimer’s and diabetes. It seems that caloric restriction helps sirtuins work better within the body.

 

Personal Genomics

Personal genomics is a branch of genomics which is concerned with the analysis and sequencing of genetic material of a person. It involves different techniques to determine the partial or full genome sequencing. Once the genotypes are known, it can be compared with the published literature to determine the probably /risk of development of certain traits or diseases. Automated sequencers have increased the speed and reduced the cost of sequencing, making it possible to offer genetic testing to consumers. Our knowledge of aging, anti-aging and its genetic basis is very useful in personalized genomics and it is presently being used in predictive medicine.

What about Cialis Soft Tabs?

Most people have heard of Cialis and it’s competitor, Viagra. Even if you have no experience with erectile dysfunction, these drugs are so popular that it is hard to escape their presence. From ad on TVs, in magazines, junk email, or even just jokes, these drugs have become a part of pop culture.

Although the popularity is likely due to the subject matter – sex – these drugs are also so popular because they work, and they were the first drugs of their kind to do so. Cialis works to treat the symptom of erectile dysfunction in men. Erectile dysfunction is very common, and can affect men at any age. It occurs when a man has problems more than 50% of the time having sex due to erections that do not last long enough, do not get hard enough, or are not achievable at all. Although surgery, implants, external devices, and therapy are sometimes alternate treatments that work well, Cialis is temporary, affordable, effective, and the most convenient option. Cialis is simply a pill you take as needed, not more than once per 24 hours. You will likely see results within 30 minutes, and can have results for as long as 36 hours. Having a trouble free, spontaneous sex life is possible once again with Cialis.

Cialis soft tabs became popular in 2005 after a successful email spam campaign. Generic medications are appealing because they are typically the exact same drug, but at up to 80% less money. Cialis soft tabs, however, are not legitimate generic drugs – they are different medications that are not legal, and are simply capitalizing off the name Cialis.

There are some problems with generic drugs. It is easier to obtain illegal generic drugs than it is brand name, and this is even easier online. Many online pharmacies are unregulated and operate outside of standards set in the United States. Generic drugs under the FDA are supposed to provide the same safety, quality, and effectiveness as the original, but oftentimes this is not true. Generic drugs are supposed to go under strict scrutiny before obtaining licensure and being available for purchase. Online pharmacies allow these steps to be passed over. Because of these things, it is easier for illegitimate medications such as Cialis Soft Tabs to become available and marketed as generic.

This is not to say all generic drugs are bad, or all online pharmacies. If you purchase generic drugs from a reputable pharmacy – online or off – you should not experience any problems. Some things to look for when choosing a pharmacy include:

  • A name you trust – look for online reviews, search for the pharmacy and rip off or scams, and ask family and friends for recommendations
  • Check for a physical address and legitimate phone number
  • Make sure they require a doctor’s prescription, and do not offer to let you use their own doctor for an “Internet exam”

Once you’ve found a legitimate and reputable online pharmacy, you can get any available prescription for much cheaper than local pharmacies – including brand name, legitimate Cialis.

Top Romantic Destinations

If you are looking for an exciting getaway for you and your spouse or partner, a romantic location can be just the destination to reignite a passion or give you quality time alone, something many couples who are dealing with ED can definitely use. Here is a list of some of the most romantic spots in the world to get you inspired in your relationship again.

Florence, Italy

While not as famous as Rome or even Venice, this romantic destination is sure to inspire the Italian in you (even if you don’t really have any in your ancestry). Spend some time in the Piazzale Michelangelo for one of the best views in the entire country after visiting the many famous museums in the area. A decadent brunch in one of the outdoor cafes is a perfect start to your day after sleeping in.

Savannah, Georgia

Prefer the warmth? Then head south to this lovely historic town in Georgia that’s the perfect example of old Southern charm. Enjoy romantic carriage rides around the city and spend the night in a gorgeous bed and breakfast. There are plenty of outdoor activities to enjoy on sunny days or museums to investigate in chilly or rainy weather.

Kauai, Hawaii

Instead of heading to Honolulu or other populous Hawaiian cities, take a walk on the wild side in Kauai. As one of the least developed islands, Kauai offers the perfect blend of tropical paradise, hospitality and privacy… meaning plenty quality alone time for the two of you. While there is a lot of beach to explore, you can also head inland to enjoy the exquisite mountains and waterfalls.

St. Moritz, Switzerland

If you want to try a new experience that doesn’t involve getting sand in your swimsuit, go skiing in this lovely resort town. Enjoy a brisk day out on the world-famous slopes followed by a quiet evening snuggled up by the fire gazing into each other’s eyes while sipping a hot toddy. Pack your sildenafil for this adventure so you can enjoy all of the romance you can handle.

Koh Tao, Thailand

If time and money are no issue, then exotic Koh Tao is a must-see place for couples. It’s especially exciting for those who love adventure and don’t want to spend all of their time lying on a beach. Of course, you can also do that here, but you also have the opportunity to go scuba diving or hiking. Then, spend an evening watching the sunset over the water with a delicious dinner.

Whether you are looking for a weekend getaway or a week-long trip for romance, there are plenty of wonderful places to choose from, both near and far. Even a weekend trip to a nearby hotel can feel like a vacation if you plan it right. Pack your Sildenafil and your best cologne and bring back the romance in your relationship.

Treating ED and more with Cialis

Cialis is a very popular drug when it comes to erectile dysfunction treatment. By providing an effective treatment for high blood pressure and other conditions Cialis could be even more useful according to recent research.

Cialis, which is manufactured by Lilly Icos, contains the active ingredient tadalafil. This component was discovered to be an effective way of treating high blood pressure, as well as keeping certain prostate conditions under control, and can help treat an impending lung disorder.  Both Lilly Icos and humans will gain more benefits from this.

The Senior Vice President of Lilly Icos stated at a recent press release that the company is always working to develop tadalafil as a treatment for other conditions. Cialis has always been targeted for other disorders with it being in development as an angina treatment before it was used as an erectile dysfunction treatment.

Lilly Icos has officially announced that it will use the mechanism of tadalafil in order to effectively treat chronic high blood pressure, which is also referred to as hypertension. There are currently more than 50 million people suffering from hypertension in the United States alone. There are many drugs available to treat hypertension, but all of them have major side effects. Cialis also has a risk of side effects, but they are usually much less severe and occur much less frequently – which means Cialis might become the best treatment for hypertension that is available.

Cialis is not yet ready to be used as a high blood pressure treatment, however. Lilly Icos recently put Cialis through a phase 2 study in order to see the results of Cialis on people with hypertension. The results were found to be clinically significant and established that Cialis is comparable in effect with other drugs currently on the market. The only difference noted was in side effects. Other hypertension drugs interfere with your sex life, but Cialis has the opposite effect.

In addition to hypertension, Cialis can also treat Benign Prostatic Hyperplasia. Benign Prostatic Hyperplasia is a common prostate condition, and after a patient with this condition was given a dose of Cialis, they showed statistically significant improvements.

Finally, Cialis can be an effective treatment for pulmonary arterial hypertension, which is a rare disorder that occurs when a person experiences increased pressure in the arteries in the lungs. People who have this condition do not typically survive longer than three years, and it typically occurs in people under 30 years old. Patients with pulmonary arterial hypertension typically experience shortness of breath, heart failure, and fatigue. The current drugs available to treat this disorder have negative effects on the liver. Currently, the FDA has approved sildenafil (the main ingredient in Viagra) to treat this condition, which sparked the interest in tadalafil – which seems to be a promising treatment as well.

If you are interested in Cialis as a way to treat erectile dysfunction, or any of the other potential conditions, speak with your doctor. He or she will be able to provide you with more information and give you a prescription if Cialis seems like a good fit for you.

ED Medicine online: a basic guide for beginner users

Erectile dysfunction is a common sexual problem that affects men of all ages. In addition to a poor sex life, erectile dysfunction can cause other problems such as anxiety, guilt, stress, depression, and low self-esteem. Due to these negative effects, treatment for erectile dysfunction is very important. However, many men skip out on treatment for a variety of reasons. More men can be helped to have access to this fantastic drug by purchasing Viagra online. Before you begin purchasing Viagra online or using it here is some information to know first.

Viagra online is offered through many different pharmaceutical websites and generic options are just as prevalent. Although the medication can be found at many online pharmacy websites and it may be hard to choose one, pharmacy reviews alleviate some of the stress with that decision. Whether to go for the full price name brand medication or choose a cheap generic product is the real choice.

Knowledge of how the drugs work is info is much more needed than more people think so, in particular customers who are under the impression that they will get an erection merely by taking the drug and often times have the impression they will have improved their sexual prowess by doing so. The truth is that sildenafil citrate, which is the active ingredient in Viagra and many generic options as well, has a basic and straightforward mechanism of action. The drug is a PDE5 inhibitor drug. PDE5 is an enzyme that blocks the blood flow to your penis. By preventing the activation of this enzyme, the drug helps in keep the blood flow consistent throughout sex. People who buy generic Viagra online are able to enjoy their arousals by having an augmentation of cGMP levels in the body. This chemical keeps the smooth muscles flexible, leading to wide arteries that are large enough to carry enough blood to the required locations.

When you buy generic Viagra online, it is important to keep in mind that it does not produce an erection directly, nor improves your interest in a sexual partner. However it does open up the blood vessels so the blood can flow more freely to the penis, which it in turn can use to become and stay erect. This does not mean that the actual stimulation does not have to occur or that any hypersensitivity will occur. Arousal is required for the proper activation of the medication; the same as it would be were you not suffering from erectile dysfunction. This makes it easy to spot cheap knock offs when shopping online; avoid any drug claiming to have more desirable side effects then Viagra; i.e. aphrodisiacs and similarly sexual heightening results.

Knowing what to avoid when shopping for generic Viagra online is the easiest way to make the best decision. While some options may not offer the best results, others provide a quality substitute for a reduced price. Cheap generic options that provide comparable results are also just as common and with proper research can be easily located.

The Reasons Why Generic Cialis is the Best Option

Cialis, Levitra, Viagra – chances are you have heard of these drugs (or at least one of them), even if you yourself have no experience with erectile dysfunction. Since 1998, these drugs have taken the world by storm. Sex is a very important part of life for most people, and when there are sexual problems, many negative effects can occur. Therefore, a healthy sex life is critical, and is one of the reasons why these drugs have become so popular.

When choosing a drug, these three are the main competitors, but there are also the generic versions. Generic Cialis, Viagra, or Levitra will work in the same way, and almost be the exact same drug, as the brand name. The only difference is usually price – generic drugs are cheaper. Therefore, it is always a good idea to choose the generic version when possible.

You also have to decide on which drug would work best for you. Many men agree that Cialis (and generic Cialis) is the best one of the three. Here are some of the ways Cialis is different than its competitors:

Erectile dysfunction drugs typically work in the same way, with minor differences. In order to have an erection, you need to have proper blood flow to the penis. This increase in blood volume is what causes a hard, strong erection. The three main erectile dysfunction drugs are medications referred to as PDE5 inhibitors. This means that they work to inhibit the enzyme in your body that causes an erection to end. By inhibiting the enzyme, your body keeps your erection for a bit longer. The drugs also works by increasing blood flow to the penis and relaxing muscles (which allows the blood to flow in).

One of the main reasons a person would want to choose Cialis (or generic Cialis) over the others is the length of time to experience results. With Viagra, you will need to take a pill around an hour before sexual activity, and you will see results for 4 hours. This is nice for a planned night, but it is not so great for spontaneous sexual encounters, or for having sex multiple times in a day, as you can only take one pill per 24 hour period. Cialis, on the other hand, starts working for most men in as little as 30 minutes, and most men see results for up to 36 hours! This means you can take your Cialis pill on Friday, and have sex worry free until Sunday! This benefit is one that many men cannot pass up, and certainly helps bring back confidence and a satisfying, spontaneous sex life.

Another benefit of Cialis is dietary. You can eat and drink normally while on Cialis. With the others, food may interfere with results. However, all three drugs require you to avoid alcohol as drinking can lead to more frequent and more severe side effects.

These two benefits are minor differences, but are very important if you want to experience a more natural sex life.

Romantic Getaways for Couples in the US

When it comes to planning your vacation for just the two of you, the United States has plenty to offer to make your time together a romantic one. Whether you are looking to soak up some rays on a beach, climb a mountain, sip a cocktail in the urban nightlife or sightsee, you will find it is all here. The hard part is deciding where to go.

Hawaii

Hawaii is the state that has it all: far enough away that it will seem like you are on a romantic getaway, yet still offers the comforts and peace of mind of being in the US.

Maui is one of the most popular travel destinations in America. The island is not the biggest and it is not the smallest either. There you can find many luxury resorts or hotels that would fit your style and budget. Maui has many famous beaches to visit like Wailea Beach, to snorkeling with sea turtles, learn to hula dance from professionals, golf the coastal fairways, to exploring the world’s largest dormant volcano.

If you are looking for relaxation and solace in one of the United States’ most beautiful destinations, Kauai is just the ticket. With only two major roads and no high risers allowed, most of what Kauai has to offer is by foot. Bring your best pair of hiking boots and umbrella to enjoy breathtaking sunsets, chocolate-sand beaches and endless aquamarine skies.

Lanai offers secluded sandy beaches and plenty of off-roading en route to visit many of the island’s natural wonders. It would be well worth the visit to Lanai for adventure, beauty, and the feeling of isolation.

California

Napa Valley is definitely a place to visit without the children. This vacation hot spot, though costly, has lots of life-changing wine and luxury resorts to cater to your every need, all nestled in an intoxicating countryside that will keep you coming back for more.

Not far from Napa Valley is the hip and urban city of San Francisco. You will find hours of entertainment in the bustling city from strolling along the bay in the sun to visiting Fisherman’s Wharf and getting a glimpse of the Golden Gate Bridge. If you love art, world-class cuisine, and a little adventure, you will never get bored in the colorful quarters of San Francisco.

Monterey might be the place to visit for your romantic weekend getaway. With its laid back atmosphere and jaw-dropping coastline, there are plenty of natural wonders to see, great seafood to eat, and alluring golf courses that makes this easy going, low population town a must stop.

The East Coast

A trip to the southernmost point on the mainland of the United States will land you in Key West, Florida. While there is not a lot of beach or watersport activity there, Key West is definitely an unexpected seaside adventure. The free-spirit and live-by-the-moment atmosphere will have you throwing your itinerary out the window as you leisurely enjoy the many unique sites. Whether that is strolling down Duval Street and hitting up one of the many bars, biking around the whole island, or touring Ernest Hemingway’s Home, you are sure to find that many surprises await you during your stay in Key West.

Further north, you can slow down your pace and enjoy the peaceful 40 miles of national seashore where there is plenty of opportunity for that quality time in Cape Cod. Biking and sightseeing is a must, as well as eating endless amounts of seafood. Affordable and cozy is what makes Cape Cod a perfect couples’ retreat. Just pack your cheap Viagra and a few other essentials and you are ready to go.

Savannah and Charleston are both the epitome of southern hospitality. Life moves a little slower amidst Spanish moss and Southern accent streets with lots and lots of beautiful graveyards. The early history of the United States is prominent and you will find many tours and endless things to do and see in these southern cities. They also offer wonderful food, fried cuisine, freshly caught seafood and barbeque among a busy nightlife.

There are plenty of places for you to choose from to take that special someone. Just grab your cheap Viagra and pick a place to reconnect and rekindle your love.

Looking online to buy ED Medicine cheaply

Buying medication online has become quite easy over the last few years, with numerous Internet pharmacies available to choose from. Here are some things you need to know about getting the best deal.

Why Buy Online

You will find several benefits to buying your medication online. First, it is much more convenient than going to your local pharmacy. You can shop anytime instead of having to pay attention to store hours. With a local pharmacy, you have to think about traffic patterns and avoid the busiest times of day. Even 24-hour locations are not always convenient. Do you really want to get back out late at night after everything else is done to go pick up medicine?

Aother benefit is in cost savings. When you shop online, you often pay a lower price. That is because Internet pharmacies do not have the overhead that brick and mortar stores do so they can offer a lower price. In addition, they have more competition. They have to be concerned about all other online pharmacies and not just the one across town.

How to Best Use Online Pharmacies

Prices should be compared when shopping online for discounted medications like Viagra. It doesn’t mean that you will pay the same price everywhere just because one online pharmacy posts a price. Some online companies offer discounts or special deals for new customers.

While you can check out each site individually and compare prices, it is often easier and less time consuming to use a comparison site. With that site, you just enter your information one time and wait for the results. Compare prices and other data among different sites to get the best deal. Don’t forget to include shipping costs when comparing prices.

Just like your local pharmacy you will need a prescription to use reputable online pharmacies. You should stay away from any internet site that does not require you to have a prescription. Even if it has the lowest prices, you may not be receiving a quality service.

What to Look for in an Online Pharmacy

It’ simportant make sure you are dealing with a reputable pharmacy when you purchase cheap Viagra. The best way to do that is to visit a comparison shopping site and find the two or three places with the lowest prices. Then, do some more work.

  • Check out each site.
  • Find out about contact information and if a location is mentioned. Even without a traditional storefront, the company should be based out of somewhere.
  • Find out if there is a pharmacist on staff to answer your questions. Even if you have been on the medication for years, you want to know that there is someone if you should ever need them.
  • Check to see how they take payments. They will most likely allow credit cards and possibly PayPal. The page where you enter your information should be secure. To determine if this is the case, look to see if it says https in the URL. Http is not secure, but https is.

Find out if the site offers any kind of guarantee. Many reputable sites will post this in a location that is easy to find, but it should at least be on the shopping page. This can give you peace of mind when you are trying out a new site.

All of these qualities help give the site more credibility.

Knowing where to buy Viagra online is be a fabulous way to save money. Just make sure you compare prices and websites to get the best deal and to be safe. It may end up being the way you buy all of your medication for convenience and cost savings.

Prednisone helps PMR patients

Prednisone is one of those drugs that can be easily called “jack of all trades”. The spectrum of its applications is very broad and comprehensive, including various conditions characterized by inflammatory processes in the body. And it’s not surprising to learn that Prednisone is extensively used for the treatment of polymyalgia rheumatica, a painful condition common among senior patients. But if you’re looking forward to using this drug as a way to alleviate this health problem you should learn more about the condition and understand how Prednisone can actually help you.

Polymyalgia rheumatica or shortly PMR is an inflammatory health condition characterized by instant impulses of acute pain that mainly affect joints in the shoulder or hip areas. It is more common in women than men and is diagnosed mainly in people over 60 years old. The actual causes for this condition are still unknown as there’s no obvious pathogen or other agent to trigger the pain. There are various theories including viral influence and other factors, but they are more speculative rather than applicative. The actual treatment of this condition usually involves the use of corticosteroid drugs such as Prednisone, which delivers the best effects in managing the condition in the long term.

Prednisone is a well-known corticosteroid medication and it’s not surprising to see it being prescribed to virtually all patients suffering from polymyalgia. In fact, the drug is probably the only viable option available, because other anti-inflammatory medications such as NSAIDs do not deliver effects that would be on the scale with Prednisone. Nevertheless, such common drugs as ibuprofen may be prescribed in conjunction with corticosteroids for getting better results with lower doses of the steroids in the long run. It is therefore very important to understand the potential hazards of misusing Prednisone and learn how it should be used correctly.

Since Prednisone is a corticosteroid drug it has a very complex effect on the entire body, mainly targeting the immune system. It acts as an immunosuppressant, which means that the drug weakens the immune system and makes it less active. The good thing about such effects is that virtually all inflammatory processes can be stopped or at least alleviated. But on the other hand, this makes the organism more susceptible to diseases and infections as the immune system cannot respond to various agents as actively as it has to. So it is a very common recommendation to watch out for any infection hazard while taking Prednisone, especially during a long-term treatment – something PMR actually implies.

But if you want to relieve the symptoms of polymyalgia without relying heavily on Prednisone and other prescription drugs, you may want to try adopting some lifestyle changes. It was observed that regular exercises reduce the risk and impact of PMR, probably because well-flexed muscles are less likely to suffer from sudden pain. Diet is another point of interest, as it can also reduce the intensity of PMR. A balanced diet rich with vitamins and minerals is thought to provide anti-viral effects and regulate the immune system. Of course, these effects will take much longer to manifest and won’t be as pronounced as with drugs like Prednisone. But it’s definitely a good way to address PMR without taking higher doses of the prescription medication.

Cialis – the famous Weekend Pill

There are very few drugs that actually get a nickname among its users. Back in the day Viagra was called the Blue Pill and anyone who used it would give you a knowing smile if the subject would be brought up. Today there’s another pill that has earned a nickname of its own – Cialis. And judging by the rate at which the number of its users is growing year after year it becomes apparent that there’s a new leader on the market of ED medications, which is not surprising given the fact that people call it The Weekend Pill. The nickname describes the drug’s effects very accurately so it’s no wonder why people choose Cialis over other similar drugs. But let’s see if the pill actually lives up to its reputation.

The term “weekend pill” has become quite widespread in the first several years after Cialis has been introduced to the market in 2003. When compared to other prescription drugs available at the moment, Cialis looked like an ED medication on steroids – it acted faster and lasted for much longer. And it’s the long-lasting effect that actually earned the drug its nickname, since many of its users have rapidly realized that they could enjoy an entire weekend of perfect erections with just a single pill taken on Saturday. Given the official duration of effects that lasts for up to 36 hours it’s quite easy to understand that such a claim is quite plausible. Of course, in some men the effects of Cialis may last for a shorter period of time, making it hard to get away with just a single pill for the entire weekend. But when compared to the usual 4-6 hours with Viagra or Levitra, it’s quite obvious that Cialis really stands up to its reputation among ED drug users. And it is actually possible to get more out of it if the drug is used correctly and wisely.

For many men the weekend is a time when they can allow themselves to relax on a short sabbatical, giving little attention to diet, sobriety or physical activity. It’s when they allow themselves to spend a day on the couch, eating pizza, watching a game and drinking some beer. And while such a method of relaxation can be well-deserved by a hard-working men who spends his entire week in the office, there are very unpleasant implications involved if it becomes systematic. Lack of physical activity, diet consisting of junk food, alcoholism, tobacco smoking and drug abuse are some of the most common lifestyle-related causes for the development of ED in the first place. So if you’re using Cialis for keeping your erections firm in the bedroom during the weekend, taking such a form of relaxation as described above is simply sabotaging your own treatment. Sure, everyone needs to relax every once in a while, and you definitely wouldn’t go to the gym on the weekend. But taking a more careful approach towards own lifestyle and diet is one of the most important aspects of preventing ED and improving the effectiveness of Cialis. So if you actually want to get more out of the Weekend Pill, take a moment to think about how your weekends are spent. Maybe there are things you shouldn’t do too often if you really want to enjoy great sex with hard erections.